Patent-Pending Delivery Platform

Peptides
that survive
long enough
to work.

OpenEye Labs engineers nano-encapsulated intranasal and sublingual spray systems that protect peptide integrity through manufacture, storage, and mucosal delivery — without needles, without cold chain, without compromise.

FDA-Registered FacilitycGMP Compliant12-Month Room-Temperature Shelf Life60–80% Mucosal Bioavailability

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A Vertically Integrated Laboratory

We build the molecule, the formulation, and the system that delivers it.

OpenEye Labs is an FDA-registered, cGMP-compliant laboratory specializing in peptide synthesis, formulation chemistry, and proprietary delivery-system engineering for the professional wellness and clinical compounding channels.

Our work spans the full continuum — from active synthesis and extraction, through supramolecular formulation design and nano-encapsulation, to packaged finished goods and IP creation. Every product we develop is built around a single conviction: the delivery system is as important as the active itself.

Synthesis

Peptide and small-molecule synthesis to clinical-grade specification.

Extraction

Botanical and biological extraction for active and excipient streams.

Formulation

Route-specific formulation chemistry tuned to mucosal physiology.

Delivery Systems

Nano-encapsulated intranasal and sublingual sprays, plus transdermal serums.

Supramolecular Biochemistry

Host-guest inclusion-complex design for peptide protection and transit.

Nano-Encapsulation

Proprietary cage chemistry for actives across the molecular weight range.

Peptide Science

Stability, conformation, and bioavailability engineering for peptide actives.

Nutraceutical R&D

Active development for the cash-pay clinical wellness channel.

Product Development

From bench formulation to finished, packaged, channel-ready SKU.

IP Creation

Patent-pending platform chemistry and formulation IP held in-house.

Research & Development

In-house R&D program targeting next-generation delivery and stability.

Channel Engineering

Custom formulations and white-label development for partner pipelines.

The Delivery Platform

Two architectures.
One science.

Mucosal delivery is not one problem. The intranasal epithelium and the sublingual mucosa absorb very different molecules through very different mechanisms — so we engineered two distinct delivery architectures under a single platform, each tuned to the tissue and the molecular weight class of its actives.

Intranasal Architecture

Direct paracellular transit through the nasal epithelium.

Engineered for smaller-to-mid-weight peptides where vascularized nasal mucosa offers the fastest systemic onset. Bypasses first-pass hepatic metabolism entirely.

Encapsulation

Single-cage molecular inclusion complex shields the active from enzymatic and oxidative degradation through transit.

Permeation

Superior permeating excipients drive paracellular transit across the nasal epithelium, improving uptake without tight-junction disruption.

Residence

Mucoadhesive polymer matrix extends residence time on the mucosal surface, slowing ciliary clearance so the dose is absorbed, not washed away.

Buffer

Amino-acid buffer system holds pH 5.3 ± 0.1 — the narrow window where peptide stability and mucosal compatibility intersect.

Optimized For

Selank, Semax, Tesamorelin, Ipamorelin, and other peptides in the small-to-mid molecular weight range.

Sublingual Architecture

Engineered for the larger molecules nasal can't carry.

Built for higher molecular weight peptides — metabolic agonists, regenerative blends, recovery actives — where the sublingual epithelium and richer surface area open absorption pathways the nasal route can't access.

Encapsulation

Dual-host inclusion complex — a complementary multi-cage chemistry that fully shrouds molecules too large for any single host cavity. The defining IP for the sublingual line.

Permeation

Membrane-fluidization permeation enhancer transiently opens tight junctions 7–10×, disrupting epithelial lipid packing to permit transit of the complete encapsulated complex.

Residence

Mucoadhesive cellulose-based matrix extends sublingual residence time so absorption completes before the active is swallowed.

Buffer

Amino-acid buffer system holds pH 5.6 ± 0.1 — tuned to oral mucosa rather than nasal.

Optimized For

GLP-2T, GLP-3R, BPC-157, TB-500, NAD+, MOTS-c, SS-31, and similar high-MW or polar actives.

The Bioavailability Advantage

Closing the gap between
oral and injectable.

Conventional oral peptide delivery sacrifices most of the dose to GI degradation and first-pass hepatic metabolism. Standard saline nasal sprays clear the mucosa before meaningful uptake can occur. Our nano-encapsulated platform was engineered specifically to close the absorption gap to injectable while keeping the patient experience needle-free.

5–20%

Oral Tablets / Capsules

Most of the peptide dose is lost to stomach acid, GI proteases, and first-pass hepatic metabolism before reaching circulation.

20–40%

Standard Saline Nasal

No encapsulation, no permeation engineering — rapid mucociliary clearance limits actual systemic uptake. Standard saline sprays are only stable for up to 30 days.

60–80%

OpenEye Sublingual

Dual-host encapsulation + 7–10× tight-junction modulation + mucoadhesive residence — engineered for larger molecules.

60–80%

OpenEye Intranasal

Single-cage encapsulation + extended residence time via mucoadhesive polymer + superior permeating excipients — engineered for nasal mucosal physiology.

~97%

Subcutaneous Injection

The clinical reference standard — at the cost of needles, sharps protocol, cold chain, and patient adherence loss.

Our delivery architecture is engineered to reach the absorption performance of injectable peptides while preserving the patient experience and clinical adherence profile of a simple spray. Channel data consistently shows higher reorder cadence and lower mid-program drop-off versus injectable comparators.

The Six-Layer Protection Architecture

A peptide is only as effective
as the system that protects it.

Every OpenEye Labs formulation is built around six engineered protection layers — designed to keep the active intact from the moment it's compounded, through twelve months on the shelf, all the way to mucosal absorption.

Molecular Encapsulation Cage

Proprietary inclusion-complex chemistry shrouds peptide active sites from proteases, oxidative attack, and aqueous degradation. A complementary multi-host architecture is deployed for larger molecules where single-cage geometry cannot fully enclose the active.

Clinical ImpactPeptide integrity preserved from fill line to absorption site.

Oxidative Shield

A dual-pathway antioxidant system intercepts both metal-catalyzed and radical-mediated oxidation. Inert-atmosphere fill at packaging eliminates dissolved oxygen at the start of shelf life — closing the loop on the most common peptide degradation pathway.

Clinical ImpactNo oxidative drift across the full 12-month dating period.

Thermal Stability Matrix

An extremophile-inspired glycomatrix preserves peptide tertiary structure across ambient temperature variation. No cold chain. No refrigeration. No compliance loss from patient mishandling — the formulation is engineered to absorb thermal stress.

Clinical ImpactRoom-temperature shipping and storage. Simplified dispensing.

pH-Lock Buffer System

A biocompatible amino-acid buffer holds the formulation within the narrow stability window peptides require, resisting drift across the entire shelf life. The buffer is tuned per delivery route — 5.3 for nasal, 5.6 for sublingual — to match mucosal physiology.

Clinical ImpactPredictable potency from first dose to last.

Mucosal Permeation Engineering

A route-specific permeation strategy. The intranasal architecture extends nasal residence time and provides superior permeation across the epithelium. The sublingual architecture combines 7–10× tight-junction modulation with the dual-host encapsulation system to permit transit of larger metabolic and recovery peptides.

Clinical ImpactMeaningful systemic absorption without needles.

Mucoadhesive Residence Matrix

A bioadhesive polymer matrix extends contact time with the absorptive epithelium so the active is taken up rather than cleared. Tuned per route — nasal mucoadhesive for ciliary resistance, sublingual mucoadhesive for swallow-reflex resistance.

Clinical ImpactMore of the dose reaches systemic circulation.

Formulation Highlights

For the colleagues who read formulations
before they prescribe them.

We make these specifications visible because the audience that matters most to us — practicing clinicians and compounding pharmacists — actually reads them. The depth of a formulation is its credibility.

Full COAs, batch records, and stability data are available to authorized accounts on request.

Manufacturing

FDA-registered facility, cGMP compliant

Active Grade

USP-grade where applicable, COA per lot

Excipient Class

GRAS-status throughout the formulation

Buffer System

Amino-acid biocompatible, route-tuned

Preservative

Phenoxyethanol-based, mucosa-compatible

Nasal Base

No ethanol, no phosphate, no citrate

Surfactant Level

Micro-surfactant only, sub-irritation threshold

Atmosphere

Argon or nitrogen blanket at packaging

Shelf Life

12 months from manufacture date

Storage

Room temperature, 59–85°F, no refrigeration

Documentation

Batch records retained per cGMP requirements

Custom Work

White-label and co-branded development available

Shelf Stability

Twelve months.
No fridge.

Every OpenEye Labs formulation is engineered to hold its potency for twelve full months at standard room temperature. No cold-chain logistics. No refrigerated shipping. No patient education on storage protocol. No compliance loss when a bottle gets left on a countertop.

The thermal stability matrix, the oxidative shield, the pH lock, and the encapsulation cage work as a single integrated system — each layer compensating for the failure modes the others can't catch.

12 mo

Shelf Life from Manufacture

59–85°F

Room-Temperature Storage

Cold-Chain Required

Standard

Shipping & Dispensing

Built For

The clinicians who
scrutinize formulations.

Two audiences read OpenEye Labs spec sheets with the most attention to detail. We've built the platform — and the documentation behind it — around what each of them actually cares about.

For Physicians & Clinics

Adherence is the
silent variable.

You can prescribe the perfect protocol and still lose the outcome to a patient who quietly stops injecting at week three. Our delivery platform was designed around the friction points that drive mid-program drop-off — and the economics that follow.

Needle-free administration removes the most common patient-side barrier to starting and continuing a protocol.
Room-temperature storage means no fridge logistics, no cold-chain education, no patient compliance loss to mishandling.
Predictable, stable potency across the full 12-month shelf life — first dose to last, no degradation drift.
Consistent absorption profile supports protocol design and outcome reproducibility across patient cohorts.
Stronger reorder cadence and lower mid-program drop-off protects program revenue and patient results.

For Compounding Pharmacists

A formulation worth
dispensing.

The depth and discipline of a formulation is what separates a credible peptide product from a marketing exercise. Every spec on our sheet is engineered to satisfy the level of scrutiny a working pharmacist actually brings.

FDA-registered, cGMP-compliant manufacture with full batch documentation retained per regulation.
COAs available per lot. Stability data, microbial limits, and identity testing on file for authorized accounts.
GRAS-status excipients throughout. USP-grade actives where applicable. No questionable formulation choices.
Room-temperature stability eliminates refrigerated dispensing real estate and simplifies patient counseling.
White-label and co-branded development available for pharmacy partners with their own clinical channel.

Six SKUs.
Six wellness pathways.

Every product in the line is built on the same patent-pending delivery platform — engineered, encapsulated, and stabilized to the same standard. Custom formulations and white-label configurations are available at minimum order thresholds.

NAD+ · MOTS-c · SS-31

Cellular energy, mitochondrial wellness, and active-aging support. The flagship combination behind our most demanding sublingual architecture.

GLP-2T

Metabolic-support sublingual spray for provider-supervised programs centered on appetite, satiety, and body composition.

GLP-3R

Premium metabolic-support sublingual for advanced wellness programs. Comprehensive appetite, energy balance, and body composition.

BPC-157 · TB-500

Recovery and performance sublingual spray for active-lifestyle, mobility, connective-tissue, and post-activity wellness programs.

Selank · Semax

Cognitive performance and stress-resilience nasal spray for focus, mental clarity, and executive wellness programs.

Tesamorelin · Ipamorelin

Body-composition and recovery nasal spray for supervised wellness programs focused on lean-mass support, sleep quality, and recovery routines.

→ Custom peptide and blend formulations available · 1,000-unit minimum per SKU · White-label and co-branded configurations supported

Quality & Compliance Posture

Documented to the standard
your accounts will demand.

Registration

FDA-Registered Facility

Manufacturing site registered with the U.S. Food and Drug Administration.

Compliance

cGMP Standard

Current Good Manufacturing Practice protocols across every production run.

Documentation

COA Per Lot

Certificate of Analysis available to authorized accounts per production lot.

Traceability

Full Batch Records

Manufacture, fill, and release records retained per cGMP requirements.

Packaging

Inert-Atmosphere Fill

Argon or nitrogen blanket at packaging eliminates dissolved oxygen.

Logistics

Standard Shipping

No cold-chain required. Room-temperature stable for twelve months.

Patent-Pending Platform

Proprietary nano-encapsulation chemistry, formulation IP held in-house.

Capability

Custom Development

Single peptides, custom blends, and private-label configurations.

Open an Account

Three partnership paths.
One platform.

OpenEye Labs partners directly with licensed physicians and clinics, compounding pharmacies, and authorized distributors. Pricing, account terms, COAs, and partnership documentation are available upon inquiry.

Physicians & Clinical Practices

Compounding Pharmacies

Wholesale Distributors

Peptidesthat survivelong enoughto work.